Daniel 11:20

He is talking about Antiochus Epiphanes, who on his return from Rome succeeded his brother Seleucus. Seleucus (called Philopator) succeeded Antiochus the Great, since he was his son. When Seleucus died, Antiochus Epiphanes received the throne. He says about the latter, "From his root kingship will sprout, and he will put aside his readiness." That is to say, he will imitate his father's power and will be adequate to lay hold of the kingdom readied by his father.

He was in fact not glorious, seeming instead to be an insignificant figure, because he was kept under guard in Rome. "And he will return, and he will gain mastery over a kingdom by his cunning." But, nonetheless, especially since he had been brought down to nothing, he will come with great advantage and a very large army, and he will overpower the kingdom with deceit as its helper, and he will use gross deceit all the more. The blessed Daniel saw this fact also in the second vision, and he heard holy Gabriel saying, "Guile is in his hand, and he will become arrogant in his heart. He will destroy many, and he will prevail as many are destroyed." Thus, he says here words to the same effect: "He will gain mastery over a kingdom by his cunning."

Verse 20. "And there shall stand up in his place one most vile and unworthy of kingly honor, and in a few days he shall be destroyed, not in rage nor in a battle." The reference is to the Seleucus surnamed Philopator, the son of Antiochus the Great, who during his reign performed no deeds worthy of Syria or of his father, but perished ingloriously without fighting a single battle. Porphyry, however, claims that it was not this Seleucus who is referred to, but rather Ptolemy Epiphanes, who contrived a plot against Seleucus and prepared an army to fight against him, with the result that Seleucus was poisoned by his own generals. They did this because when someone asked Seleucus where he was going to get the financial resources for the great enterprises he was planning, he answered that his financial resources consisted in his friends. When this remark was publicly noised abroad, the generals became apprehensive that he would deprive them of their property and for that reason did him to death by nefarious means. Yet how could Ptolemy be said to rise up in the place of Antiochus the Great, since he did nothing of the sort? This is especially improbable since the Septuagint translated: "And there shall stand up a plant from his root," that is, "of his issue and seed," who should deal a severe blow to the prestige of the empire; "and within a few days he shall be destroyed without wrath or battle." The Hebrews claim that it is Trypho who was intended by the man who was most vile and unworthy of kingly honor, for as the boy-king's guardian he seized the throne for himself.