Ephesians 5:20

We are told to give thanks to God for all his gifts. For God has stooped low to adopt us through Christ his own Son, through whom we know God. We have learned that God, being Spirit, is to be adored in the Spirit. So we submit ourselves to one another out of reverence for Christ, who commanded us to pursue humility.

Paul now calls us to "give thanks always and in everything." This is to be understood in a double sense, both in adversity and in good times.… In this way the mind rejoices and bursts out in gratitude to God, not only for what we think good but for what troubles us and happens against our will.… It is obvious that generally we are called to give thanks to God for the sun that rises, for the day that goes by and for the night that brings rest … for the rains that come, for the earth that brings forth fruit and for the elements in their course.… Finally, we are thankful that we are born, that we have being, that our wants are sufficiently taken care of in the world, as if we lived in the house of an extremely powerful family patriarch, knowing that whatever is in the world has been created on our account. In this way we give thanks when we are grateful for the benefits that come to us from God. All these things, however, the heathen also does, and the Jew and the publican and the Gentile. But the second sense of giving thanks is seen in the special gift of Christians to give thanks to God even in seeming adversity.… Those who are saintly in their own eyes are prone to give thanks to God because they have been released from dangers and afflictions. But according to the apostle the greater virtue is to give thanks to God precisely amid those very dangers and afflictions.

That is, "let your requests be made known unto God, with thanksgiving" (Phil. iv. 6); for there is nothing so pleasing to God, as for a man to be thankful. But we shall be best able to give thanks unto God, by withdrawing our souls from the things before mentioned, and by thoroughly cleansing them by the means he has told us. What then? Are we to give thanks for everything that befalls us? Yes; be it even disease, be it even penury. For if a certain wise man gave this advice in the Old Testament, and said, "Whatsoever is brought upon thee take cheerfully, and be patient when thou art changed to a low estate" (Ecclus. ii, 4); much more ought this to be the case in the New. Yes, even though thou know not the word, give thanks. For this is thanksgiving. But if thou give thanks when thou art in comfort and in affluence, in success and in prosperity, there is nothing great, nothing wonderful in that. What is required is, for a man to give thanks when he is in afflictions, in anguish, in discouragements. Utter no word in preference to this, "Lord, I thank thee." And why do I speak of the afflictions of this world? It is our duty to give God thanks, even for hell itself, for the torments and punishments of the next world. For surely it is a thing beneficial to those who attend to it, when the dread of hell is laid like a bridle on our hearts. Let us therefore give thanks not only for blessings which we see, but also for those which we see not, and for those which we receive against our will. For many are the blessings He bestows upon us, without our desire, without our knowledge. And if ye believe me not, I will at once proceed to make the case clear to you. For consider, I pray, do not the impious and unbelieving Gentiles ascribe everything to the sun and to their idols? But what then? Doth He not bestow blessings even upon them? Is it not the work of His providence, that they both have life, and health, and children, and the like? And again they that are called Marcionites, and the Manichees, do they not even blaspheme Him? But what then? Does He not bestow blessings on them every day? Now if He bestows blessings on them that know them not, much more does he bestow them upon us. For what else is the peculiar work of God if it be not this, to do good to all mankind, alike by chastisements and by enjoyments? Let us not then give thanks only when we are in…