Matthew Henry on Isaiah 64:6–end
As we have the Lamentations of Jeremiah, so here we have the Lamentations of Isaiah; the subject of both is the same - the destruction of Jerusalem by the Chaldeans and the sin of Israel that brought that destruction - only with this difference, Isaiah sees it at a distance and laments it by the Spirit of prophecy, Jeremiah saw it accomplished. In these verses,
I. The people of God in their affliction confess and bewail their sins, thereby justifying God in their afflictions, owning themselves unworthy of his mercy, and thereby both improving their troubles and preparing for deliverance. Now that they were under divine rebukes for sin they had nothing to trust to but the mere mercy of God an…
Read the whole note in the consoleJamieson-Fausset-Brown on Isaiah 64:10
holy cities--No city but Jerusalem is called "the holy city" (Isa 48:2; Isa 52:1); the plural, therefore, refers to the upper and the lower parts of the same city Jerusalem [VITRINGA]; or all Judea was holy to God, so its cities were deemed "holy" [MAURER]. But the parallelism favors VITRINGA. Zion and Jerusalem (the one city) answering to "holy cities."
Adam Clarke on Isaiah 64:9
Neither remember iniquity - For לעד תזכר laad tizcor, one of my MSS. has לעד תקצף laad tiktsoph, "be not angry," as in the preceding clause. This has been partially obliterated, and תזכר tizcor, written in the margin by a later hand: but this MS. abounds with words of this kind, all altered by later hands.
John Gill on Isaiah 64:10
Thy holy cities are a wilderness,.... Meaning either Zion, the city of David, and Jerusalem; the one called the upper, the other the lower city; now uninhabited, and a mere wilderness: or else the other cities of Judea, in which were formerly synagogues for religious service, and in which dwelt many godly families where the worship of God was kept up; but now a desert, at least quite devoid of true religion and godliness.
Zion is a wilderness, Jerusalem a desolation; which are either explanative of the holy cities in the preceding clauses, or are mentioned as distinct from them; the account proceeding from the lesser to the metropolitan cities, which fared no better than they did, but equal…